what... are... you... READING

[Lestat]

I like stephen king's books, never could get into that one at all. I can't think of many times I've returned a book to a library mostly unread before.

Currently reading a few articles on kappa opioid receptor agonists and antagonists.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             

[odeon]

I like this one, I have to say.

[TheoK]

I prefer his older books. In his later books he has too many details and too much "supernatural" (he has "supernatural" in most books, but not with a zillion details) and some way he writes like a very old man, although he is just 65 years old.

[MissKitty]

I'm still trying to finish The Prince of Tides by Pat Conroy. Normally I read really quickly but this was a slow read for me. Good storyline but I don't know...it drags on. Only 100 pages left.

I have 22 books on my "to read" list. Not sure what I'll read next. 

[Lestat]

Some interesting bedtime reading

Herkinorin looks very interesting indeed. Beta-arrestin 2 Doesn't appear to be the only mechanism in play in terms of opioid tolerance, conditioned place preference, dependence liability, there are other factors, such as cholestocystokinin receptors, ORL-1 (the nociceptin opioid-like receptorddddddddddddddddddddddddddddddddddddddd


Herkinorin Analogues with Differential Beta-Arrestin-2 Interactions
J Med Chem. 2008 April 24; 51(: 2421–2431.
 doi:  10.1021/jm701162g

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494883/?tool=pubmed


http://www.anesthesia-analgesia.org/content/101/3/728.long
The Role of Opioid Receptor Internalization and β-Arrestins in the Development of Opioid Tolerance

doi: 10.1213/​01.ANE.0000160588.32007.AD
A & A September 2005 vol. 101 no. 3 728-734


http://www.ncbi.nlm.nih.gov/pubmed/15346705
Acta Anaesthesiol Taiwan. 2004 Jun;42(2):93-101.
Opioid tolerance: is there a dialogue between glutamate and beta-arrestin? (trying to find this one for free....Gah, the amount that some of these damn publishing house middlemen want to cream off the top when supplying papers is ridiculous.


http://www.ncbi.nlm.nih.gov/pubmed/16115983/
Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in βArrestin-2 Knock-Out Mice
The Journal of Neuroscience, 1 December 2002, 22(23): 10494-10500;

[midlifeaspie]

"Duma Key", Stephen King

7/10

[TheoK]

Nah, Duma Key isn't that good. I like Blaze better. It's an old story from the 70's that he hadn't published before. Just After Sunset is also good.

[Queen Victoria]

Harry Potter and the Sorcer's Stone (4th or 5th time).

[Lestat]

Some more articles in pubmed/medline about beta-arrestin2 in the development of opioid tolerance/maintenance. Although I think I am going to lie down and refresh my brain for a while first before I start working my way way them. I'm a fast reader, but I will process better when I am fully refreshed; not to mention retain the info and develop my own theories on the research more efficiently

['andersom']

Translation of "The Century's Daughter", by Pat Barker.
Found it in the thrift-shop for €1
It's a good read.

[odeon]

"Duma Key", Stephen King

7/10

Thereabouts, so far, yes.

[Lestat]

Acute Cannabinoids Impair Working
Memory through Astroglial CB1 Receptor
Modulation of Hippocampal LTD
DOI 10.1016/j.cell.2012.01.037

[midlifeaspie]

Acute Cannabinoids Impair Working
Memory through Astroglial CB1 Receptor
Modulation of Hippocampal LTD
DOI 10.1016/j.cell.2012.01.037

Ah, those were the days.  Cannabis and astroglide 

[Queen Victoria]

Some mystery about a murder on a "who dun it" fund raiser on a boat.
One of Peg Bracken's old books - forgot how good she is.  Will post some of her stuff later
12 Steps and 12 Traditions

[Lestat]

I'm reading a pirated copy of a book on reduction techniques (chemistry that is), focusing on reduction of nitro compounds, as I have a certain beta-nitrostyrene that needs reducing to the corresponding amine. I just need to buy some solvents that are compatible with LAH to do it in.