In my fallout-tactics game, just went up against super-mutants in my first mission. Have fought them before, in twos and threes in the wastelands, only in traveling to the mission insertion point though.
Managed to take a 5 man team (well two of them are women, and one of them is a sodding great big, incredibly stealthy lizard with claws as long as a man's arm and horns that are nastier still. Too big to handle even heavy weapons like rocket launchers or machineguns, but can throw grenades and do it well (she's carrying 50+ frag grenades, plus a handful each of stun grenades, napalm grenades, a fair few molotov cocktails plus 5-6 plasma grenades, the latter having a tendency to inflict massive damage on even the toughest enemies and not even blow them to pieces, but to liquefy them and reduce them to a smoking slick of irradiated slime with a single hit.
And had the mission go well, no fatalities on the squad, which is good because I've been training them intensively, and although it was one tough damn shootout, did wipe out the mutants down to a used-to-be man. Recovered a pair of sniper rifles, 5-6 or so browning .50 cal heavy autocannon (damn monsters rival even 'mother' the deathclaw close combat lizard brute squad member in strength, and carry weapons most would use mounted on an APC or fire from a tank or other vehicle mount)
Recovered ~40something heavy machineguns of two different types, M60s and SAWs, and after extensive and careful demining operations, recovered at least 24 antitank mines plus some lighter antipersonnel-mid-range antivehicle mines. ATM there is only one squad member who can both use guns and is strong enough to wield the .50 browning, but damn is she ever dangerous packing the thing, one burst is enough to pulverize an entire squad of fairly tough enemy troops. And thats using the regular armor-piercing ammunition. For the really nasty customers, although they are scarce in terms of availability, for getting out of a tight spot, got a few hundred depleted uranium rounds as well that are more than capable of chewing heavily armored troops into meatpaste, or robotic enemies to scrap metal. Now got to run two more missions against these mutant monstrosities, but at least now, with the .50 cal (and the chick packing it is carrying a sniper rifle and an automatic shotgun as sidearms, plus if anything gets up close and personal and survives that lot plus a barrage of grenades, she still has a weapon called a 'ripper' thats more or less a handheld chainsaw version of a combat knife. Does more or less what it says on the tin, and rips things and people to little pieces.)
Recovered 5-6 rocket launchers too plus a good many HE rockets to fire. All the troops capable of using one are packing a rocket launcher, plus the deathclaw is carrying a LOT of extra munitions of all shapes and sizes.
So this time around, the little fuckers are after a rematch. But with the extra hardware the squad swiped off the last lot, they are in for a LOT more than they bargained for. But best of all, I got some intel from a certain resident monarch that is worth our combined weight plus that of our families all added together in platinum. She's really made my week and put a huge smile on my face.
Thanks QV *hugs* means more than you'll ever know.